ea0032p89 | Bone and Osteoporosis | ECE2013
Markatseli Anastasia
, Lazaros Leandros
, Kostoulas Harilaos
, Sakaloglou Prodromos
, Markoula Sofia
, Tigas Stelios
, Georgiou Ioannis
, Tsatsoulis Agathocles
Introduction: Aromatase is encoded by the CYP19 gene and catalyzes the conversion of androgens to estrogens, which in turn regulate skeletal homeostasis. Polymorphisms in the CYP19 gene have been studied for their association with bone mineral density (BMD) in the general population with mixed results.Objectives: To explore the influence of the CYP19 (TTTA)n repeat polymorphism on BMD and serum levels of osteoprotegerin (OPG), receptor activator...